Switching antidepressants pdf uk

The main reasons for switching antidepressants are an inadequate. Switching between tricyclic, ssri and related antidepressants. Instructions for changing or stopping antidepressants. Pdf switching from one antidepressant to another is frequently indicated due to an inadequate treatment response or unacceptable adverse.

Fluoxetine maois mirtazapine paroxetine reboxetine sertraline trazodone. When switching between selective serotonin reuptake inhibitors, tricyclic and related antidepressants, individual patient circumstances should be considered see answer section. It is considered safer, in order to avoid precipitating drug interactions, to incrementally reduce the dose of the first antidepressant and discontinue it before. It is unnecessary if switching from fluoxetine because of the long halflife of the drug see direct switch. In the indicated instances a washout period is not essential if switching is carried out cautiously and under close observation, and clinical considerations such as illness severity support harmbenefit considerations. Antidepressants, a guide to switching and withdrawing mims. Nottinghamshire gps guide to antidepressants prescribing, swapping and stopping.

Switching from one antidepressant to another is frequently indicated due to an inadequate treatment response or unacceptable adverse effects. Antidepressants, a guide to switching and withdrawing. All antidepressant switches must be carried out cautiously and under close observation. This revision of the bap guidelines for treating depressive disorders with antidepressants anderson et al. Generally switching with another ssri before considering alternative class is the best course of action many patients who cannot tolerate one ssri will tolerate another. Ssris less likely to cause manic switch than tcasmaois. Prescribing guidelines for depression oxford health nhs. Guidelines for switching between specific antidepressants. How do you switch between tricyclic, ssri and related antidepressants. Guidelines on choice and selection of antidepressants for the. Crosstapering is an option when switching between some antidepressants, and is usually preferred to abruptly stopping the first antidepressant 2. Conservative switching strategies involve gradually tapering the first antidepressant followed by an adequate. Dsmiv diagnostic and statistical manual of mental disorders.

For advice on switching treatments please refer to the psychotropic drug. Prepared by uk medicines information ukmi pharmacists for nhs. Pdf switching and stopping antidepressants researchgate. Guidance on the use of antidepressants for the treatment of. The following table is intended for general guidance only. Uk teratology information service uktis for pregnancy and some breastfeeding. Switching and stopping antidepressants australian prescriber.